The present investigation analysed the fruits of 10 accessions of Sechiumedule(Squash) for different physico-chemical parameters. The parameters analysed included physical characteristics such as fruit color, fruit size, pulp ratio and nutritional parameters such as total sugar, reducing sugar, non reducing sugar, protein content, ascorbic acid content and crude fibre. Results indicated that the germplasm collected are rich in important nutritional parameters. The fruits analysed have very high moisture content ranging from 89.3-94.2% but are not a good source of protein which ranged from 0.77-1.05% in the fruits. The juice extracted from the fruits was rich in Vitamin C content and the Germplasm GH10 had the highest Vitamin C content (22.3%). Fruits of Sechiumedule also have significant amount of carbohydrate (4.12-4.98%), crude fibre (4.88-5.89 %) and Mineral Ash (0.245-0.321%).