Absence of resistance against diseases and insect pests in soybean is one of the main reasons for their low yield. During the kharif season, yellow mosaic epidemic damages the crop in most of the soybean growing areas of Uttarakhand. A field experiment was conducted during kharifseason of 2012-13 at N. E. Borlaug Crop Research Centre of Govind Ballabh Pant University of Agriculture and Technology, Pantnagar (Uttarakhand) for the purpose of identifying resistance in soybean germplasms, a disease screening plot, comprising of 41 test entries, was developed. Despite being highly susceptible, some test entries produced good yield and showed tolerance to yellow vein mosaic disease. Screening of forty one genotypes of soybean against White fly, Bemisia tabaci(Genn.) revealed that the soybean genotypes (1.11 per 3 plants) SL- 900 with 67.49% disease spread was found the least susceptible, followed by AMSMB- 5-18, AMS-243, AMS-MB-5-19, DS-12-5, DS-2708, DSb-16, DSb-20, JS-20-29, JS-20-34, KDS-8, KS-103, MACS-1336, MACS-504, PS-1476, PS-1477, RVS -2001-18 germplasms were found resistant to White fly infestation as well as Yellow Vein Mosaic Virus (YVMV) damage.